Mortality among hospitalized COVID-19 patients during surges of SARS-CoV-2 alpha (B.1.1.7) and delta (B.1.617.2) variantsArticle Published on 2022-11-072022-11-16 Journal: Scientific Reports [Category] SARS, 변종, [키워드] 95% CI Admission Alpha B.1.1.7 B.1.617.2 conducted contributed COVID-19 death Delta died evaluate Factor high mortality rate higher risk hospital hospitalizations hospitalized COVID-19 patient hospitalized patient hospitalized patients ICU Iran lack Nurse nutritional status occurred Patient patients with COVID-19 physician proportion risk of COVID-19 SARS-CoV-2 significantly significantly higher Tehran variant [DOI] 10.1038/s41598-022-23312-8 PMC 바로가기
Evaluation of Procalcitonin’s Utility to Predict Concomitant Bacterial Pneumonia in Critically Ill COVID-19 PatientsArticle Published on 2022-11-012022-11-15 Journal: Journal of Intensive Care Medicine [Category] 바이오마커, [키워드] Antibiotic therapy AUC Bacteremia Bacterial Bacterial infection bacterial pneumonia baseline characteristics Concomitant conducted COVID-19 creatinine Critical Critical illness Critically ill patient Culture defined determine diagnosing diagnostic ENhance evaluate group hospitalized patients ICU ICU patient identify Ill in-hospital mortality intensive care intensive care unit Mortality multivariable multivariable model no difference no significant difference offer outcome Patient PCT Pneumonia positive predict Predictive procalcitonin procalcitonin. receiver operating characteristics Regression model retrospective cohort study ROC SARS-CoV-2 secondary bacterial pneumonia serum creatinine Severe COVID-19 pneumonia Severity of disease specificity threshold utility variable vital signs was used while with COVID-19 [DOI] 10.1177/08850666221108636 PMC 바로가기
Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccinationArticle Published on 2022-10-282022-11-15 Journal: Science Immunology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Antibody Response B.1.617.2 BAL Blood booster vaccination Breakthrough infection Bronchoalveolar lavage fluid cellular immunity circulating Combination convalescent COVID-19 COVID-19 vaccine D614G Delta demonstrated effective elicit hospitalized patients humoral immune response Immunity immunization individual induce Infection mRNA vaccination mucosal neutralizing antibody Neutralizing antibody response neutralizing antibody responses offer omicron Reinfection respiratory respiratory tract response robust SARS-CoV-2 severe disease significantly lower Support T cell T cell response the SARS-CoV-2 vaccinated individuals variant variants of concern virus VOCs with COVID-19 [DOI] 10.1126/sciimmunol.add4853 PMC 바로가기
Detection and prevalence of SARS-CoV-2 co-infections during the Omicron variant circulation in FranceArticle Published on 2022-10-232022-11-15 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Admission bioinformatics circulation clinical impact Co-infection collected Delta detect detection evaluate evaluated France genetic diversity genomic hospitalized patients ICU intensive care isolate Lineage lineages omicron Patient patients Prevalence question raised random recombinants reported risk SARS-CoV-2 SARS-CoV-2 variant sets of primer Surveillance variant whole-genome sequencing [DOI] 10.1038/s41467-022-33910-9 PMC 바로가기
Mental health and chest CT scores mediate the relationship between COVID-19 vaccination status and seroconversion time: A cross-sectional observational study in B.1.617.2 (Delta) infection patientsArticle Published on 2022-10-192022-11-16 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome affecting Analysis analysis ANOVA B.1.617.2 B.1.617.2 Delta variant Chest computed tomography Chest CT China cognitive cognitive performance conducted coronavirus coronavirus disease Course COVID-19 COVID-19 pandemic COVID-19 vaccination cross-sectional Delta Depression effort emotional enrolled evaluated Health hospitalized patients immunization impairment Inactivated vaccine Infection Intervention Jiangsu Mediation analysis Mental mental health mitigate outbreak pandemic participant Patient patients Pearson correlation performed public health Quality Quality of life Regression analyses risk factor SARS-CoV-2 Seroconversion seroconversion time the SARS-CoV-2 vaccination Vaccination Status vaccination. variant was impaired [DOI] 10.3389/fpubh.2022.974848 PMC 바로가기
Observational study of factors associated with morbidity and mortality from COVID-19 in Lebanon, 2020-2021Article Published on 2022-10-192022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute kidney Admission age Analysis association Biomarker Blood Care Chronic kidney disease claimed COVID-19 COVID-19 pandemic COVID-19 patient Cox regression creatinine defined develop diabete disease effort elevated etiology evaluated Factor fatality favor Gender high mortality highest hospitalized patients independent risk factor intubation investigated Kidney function Kidney injury management morbidity morbidity and mortality Mortality observational study outcomes Patient patients performed Regression SARS-CoV-2 serum serum creatinine severe disease Shortness of breath shown significantly the disease time vaccination variable vital sign [DOI] 10.1371/journal.pone.0275101 PMC 바로가기
Effect of remdesivir post hospitalization for COVID-19 infection from the randomized SOLIDARITY Finland trialArticle Published on 2022-10-182022-11-15 Journal: Nature Communications [Category] 치료제, [키워드] 95% CI benefit confidence interval COVID-19 COVID-19 infection Effect Evidence fatigue Finnish Follow-up Hospitalization hospitalized patients hospitals joint long-COVID Long-term follow-up memory occurred outcome Pain Patient Primary outcome problem Quality of life Randomized randomized trial recruited Remdesivir reported resulting SOC Standard of care survived Symptom Symptoms Trial [DOI] 10.1038/s41467-022-33825-5 PMC 바로가기
Methicillin-resistant staphylococcus aureus nosocomial infection has a distinct epidemiological position and acts as a marker for overall hospital-acquired infection trendsArticle Published on 2022-10-112022-11-15 Journal: Scientific Reports [Category] 바이오마커, [키워드] Analysis Biomarker Care Control COVID-19 pandemic dataset disease Diseases drug-resistant Efficacy epidemiological epidemiologist HAI healthcare hospital hospitalized patients Infection lack Lower marker microbe MRSA Nosocomial infection Nosocomial infections outbreak pathogen Patient prevented reduced replaced Staphylococcus aureus Stress threshold unique USA [DOI] 10.1038/s41598-022-21300-6 PMC 바로가기
Amikacin-loaded niosome nanoparticles improve amikacin activity against antibiotic-resistant Klebsiella pneumoniae strainsArticle Published on 2022-10-032022-11-16 Journal: World journal of microbiology & biotechnology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Amikacin analyzed antibiotic Antibiotic-resistance Antibiotics Bacteria Bacterial infection Bacterial infections calculated Cell cholesterol Concentration Coverage cytotoxicity drug resistance drug-resistant evaluated Gene Expression highest hospitalized patients IMPROVE inhibited Klebsiella Klebsiella pneumoniae less MBC MDR mechanism mRNA expression multi-drug resistant Niosome Niosome. occur positive ranged reduced SARS-CoV-2 significantly Spread stability strain Strains Toxicity Treatment were measured [DOI] 10.1007/s11274-022-03405-2 PMC 바로가기
The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19Article Published on 2022-10-012022-11-16 Journal: Annals of internal medicine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI acute SARS-CoV-2 infection antibody Antigen baseline Biomarker body mass index Characteristics Clinical outcome clinically COVID-19 cross-sectional study delta variant discharge elevated ENhance enrolled Enrollment evaluate evaluated Factor Government greater higher odd hospital Hospital admission hospital discharge Hospitalized hospitalized patient hospitalized patients identify immunocompromising condition Infectious diseases Inpatient Laboratory less Level Logistic regression Male sex median Multiple multivariable N antigen nasal nasal swab Noninvasive ventilation Odds ratio operation outcome outcomes participant pathogenesis of COVID-19 pathogenesis of SARS-CoV-2 Patient patients with COVID-19 plasma Platform trial point-of-care polymerase chain predict quantification regression models Remdesivir renal impairment SARS-CoV-2 SARS-CoV-2 nucleocapsid severity speed Support Symptoms Therapeutics transcriptase viral replication was determined was measured were assessed worsened worsening [DOI] 10.7326/M22-0924 PMC 바로가기